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Phenobarbital-responsive episodic dyscontrol (rage) in dogs
N H Dodman1, K A Miczek, K Knowles
1Department of Surgery, Tufts University School of Veterinary Medicine, North Grafton, MA 01536.
Abstract:
Episodic dyscontrol (rage) was diagnosed from the clinical history, electroencephalographic findings, and response to oral treatment with phenobarbital in 3 dogs. Clinical features included a mood change heralding aggressive incidents, explosive aggression directed at people or objects, and a postaggressive phase characterized by lethargy and lack of responsiveness. Abnormal electroencephalographic findings included spike activity in the temporal recordings. All 3 dogs responded well to anticonvulsant medication with phenobarbital.
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