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Related Experiment Videos

Vancomycin-resistant Enterococcus faecium in hospitalized children.

L G Rubin1, V Tucci, E Cercenado

  • 1Division of Pediatric Infectious Diseases, Schneider Children's Hospital, Long Island Jewish Medical Center, New Hyde Park, NY 11042.

Infection Control and Hospital Epidemiology
|December 1, 1992
PubMed
Summary
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Vancomycin-resistant Enterococcus faecium (VRE) colonization is common in pediatric oncology patients. Limiting vancomycin use and using contact isolation can help prevent VRE spread.

Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Pediatric Oncology

Background:

  • Vancomycin-resistant Enterococcus faecium (VRE) poses a significant threat in healthcare settings.
  • Colonization with VRE is a precursor to VRE infections, particularly in vulnerable populations.

Purpose of the Study:

  • To determine the prevalence and risk factors for VRE colonization in pediatric oncology patients.
  • To evaluate the effectiveness of interventions in preventing VRE colonization and spread.

Main Methods:

  • A survey and case-control study design was employed.
  • Data was collected from a pediatric oncology patient population within a children's hospital.
  • Interventions included contact isolation and restriction of vancomycin prescribing.

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Main Results:

  • A high prevalence of VRE colonization was observed among pediatric oncology patients.
  • Prolonged hospitalization and the use of vancomycin and other intravenous antibiotics were associated with VRE colonization.
  • Contact isolation and vancomycin restriction were linked to the prevention of VRE colonization.

Conclusions:

  • Vancomycin use may increase the risk of VRE colonization.
  • VRE can spread nosocomially within healthcare facilities.
  • Contact isolation and judicious vancomycin use are effective strategies to prevent VRE transmission.