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Published on: December 15, 2011
Necrolytic migratory erythema as the only presenting sign of a glucagonoma
Sandra Marchese Johnson1, Bruce R Smoller, Laura W Lamps
1Departments of Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA. Johnsonsandram@exchange.uams.edu
Abstract:
We describe a 39-year-old man with a 3-year history of a recalcitrant psoriasiform eruption that was accentuated in the intertriginous areas. Hsitopathology was consistent with psoriasis. A glucagon level was 744 pg/mL with the upper limit of normal being 130 pg/mL. Computed tomographic scan of the abdomen revealed a 5-cm mass in the tail of the pancreas. The tumor was removed and found to be a glucagonoma (pancreatic islet tumor). The clinical eruption resolved promptly with surgical excision. Neither the clinical eruption nor the tumor has recurred for 6 months. The course of disease confirms the diagnosis of necrolytic migratory erythema associated with a glucagonoma.
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