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From a 2DE-Gel Spot to Protein Function: Lesson Learned From HS1 in Chronic Lymphocytic Leukemia
Published on: October 19, 2014
Cutaneous sarcoidlike lesions in B-cell chronic lymphocytic leukemia
Claude Bachmeyer1, Rima Debs, Selim Aractingi
1Département de Médecine Interne, Centre Hospitalier Laënnec, Boulevard Laënnec, B.P. 72, F-60109 Creil Cedex, France.
Abstract:
The development of systemic sarcoidosis in patients with malignancies is a well-known phenomenon. However, cutaneous sarcoidlike lesions are a rare finding. We report 2 patients with B-cell chronic lymphocytic leukemia and hypogammaglobulinemia who presented isolated cutaneous sarcoidlike lesions 9 years after the diagnosis of the hematologic malignancy in one case and after the second course of chemotherapy regimen in the other case. The role of cytokines released from malignant cells and of the hypogammaglobulinemia facilitating an unidentified infectious agent is questionable.
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