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Neonatal pemphigus foliaceus
Ranella Hirsch1, Judy Anderson, Jeffrey M Weinberg
1Department of Dermatology, State University of New York Health Science Center at Brooklyn, Brooklyn, NY, USA.
Journal of the American Academy of Dermatology
|August 2, 2003
Abstract:
The term "pemphigus" refers to a group of diseases that are characterized by the presence of cutaneous or mucosal blisters and erosions, and antiepidermal autoantibodies. There are several case reports of neonatal pemphigus vulgaris in the literature. Although pemphigus foliaceus antibodies have been shown to cross the placenta, to our knowledge, this is only the second reported case of neonatal pemphigus foliaceus. The proposed mechanism of disease transfer is the passive transfer of maternal IgG antibodies across the placenta.