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[Investigation on the gene expression pattern in cervical squamous cell carcinoma of uygur]
Kai-jiang Liu1, Ting-fang Li, Feng Zhao
1Department of Gynecologic Oncology, Affiliated Cancer Hospital of Xinjiang Medical University, Wulumuqi 830011, China.
Objective:
To investigate the differentially expressed gene in cervical squamous cell carcinoma of uygur and normal cervical tissue using gene chip.
Method:
Gene chips containing 2,048 human genes were used to investigate the gene expression pattern of 3 samples of cervical cancer.
Result:
By applying this gene chip we identified 64 differentially expressed genes in all 3 clinical cervical cancer samples, and we further identified 53 upregulated and 11 downregulated genes for functional analysis.
Conclusion:
The analysis of gene expression pattern of tumor based on gene chip can realize high-throughput screening of the genes associated with the cervical cancer.