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Related Experiment Videos

Intra-aortic balloon pumping: effects on left ventricular diastolic function.

Ashraf W Khir1, Susanna Price, Michael Y Henein

  • 1Department of Bioengineering, Imperial College, Exhibition Rd., London, SW7 2AZ, UK. ashraf.khir@brunel.ac.uk

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|August 5, 2003
PubMed
Summary
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The intra-aortic balloon pump (IABP) improves left ventricular diastolic function after cardiac surgery. IABP use significantly increases coronary artery and transmitral flow velocities, enhancing diastolic function.

Area of Science:

  • Cardiology
  • Cardiovascular Surgery
  • Biomedical Engineering

Background:

  • The intra-aortic balloon pump (IABP) is a critical temporary cardiac assist device.
  • IABP is frequently used in patients undergoing or recovering from cardiac surgery.
  • Its specific impact on left ventricular diastolic function remains incompletely understood.

Purpose of the Study:

  • To investigate the effect of IABP on left ventricular (LV) wall motion.
  • To assess the influence of IABP on transmitral flow dynamics.
  • To elucidate IABP's role in improving diastolic function post-cardiac surgery.

Main Methods:

  • Transesophageal echocardiography (TEE) with pulsed Doppler and M-mode was employed.
  • 20 post-cardiac surgery patients in ICU were studied within 36 hours.

Related Experiment Videos

  • Measurements included LAD coronary artery flow, transmitral E-wave velocity, and LV free-wall motion at various IABP assist ratios (1:1, 1:2, 1:3) and standby.

    • Main Results:

    • IABP support significantly increased peak diastolic LAD coronary artery flow velocity (P < 0.001).
    • Transmitral E-wave flow velocity and LV free-wall early diastolic lengthening velocity also significantly increased with IABP (P < 0.001).
    • Increases in transmitral flow velocity correlated strongly with LAD flow velocity (r=0.74) and LV wall motion velocity (r=0.80).

    Conclusions:

    • IABP significantly enhances diastolic LV function post-cardiac surgery.
    • Increased diastolic coronary and LV wall motion velocities contribute to improved transmitral flow.
    • The close correlation between epicardial (coronary) and intracardial (mitral) flow suggests improved LV diastolic performance with IABP.