Related Experiment Video

Updated: Aug 8, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

[Mendelson syndrome in childhood]

L C Horn1, P F Mahnke

  • 1Abteilung für Kinderpathologie, Institut für Pathologische Anatomie, Universität Leipzig.

Kinderarztliche Praxis
|December 1, 1992
PubMed

Insights

Mendelson's syndrome, a serious lung condition, was observed in an infant. This case highlights the syndrome's presentation and pathophysiology in very young children.

Area of Science:

  • Pediatric Pulmonology
  • Critical Care Medicine
  • Pathophysiology

Background:

  • Mendelson's syndrome is a rare but severe form of chemical pneumonitis.
  • It is typically associated with the aspiration of gastric contents during anesthesia.
  • Key clinical features include bronchoconstriction, pulmonary edema, and right heart failure.

Observation:

  • This report details an atypical presentation of Mendelson's syndrome in an infant.
  • The case underscores the importance of considering this diagnosis in neonates and infants with respiratory distress.
  • Morphological findings provided insights into the condition's impact at the tissue level.

Findings:

  • The study presents detailed morphological findings in an infant diagnosed with Mendelson's syndrome.
  • Pathophysiological stages relevant to this pediatric case are discussed.
  • This case expands the understanding of Mendelson's syndrome beyond its typical adult presentation.

Implications:

  • This case report may aid in earlier diagnosis and management of Mendelson's syndrome in infants.
  • Understanding the pathophysiology in this age group can inform treatment strategies.
  • Further research into pediatric aspiration syndromes is warranted.

More Related Videos

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome06:48

Fingerprinting Cardiolipin in Leukocytes by Mass Spectrometry for a Rapid Diagnosis of Barth Syndrome

Published on: March 23, 2022

Related Concept Videos

Pedigree Analysis01:35

Pedigree Analysis

Overview
Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
Sex-linked Disorders01:43

Sex-linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Lethal Alleles02:41

Lethal Alleles

Agouti: A Lethal Allele
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.