Concentration of mineral requirements in bone marrow tissue of patients with lymphoma malignum

The concentration of microelements was tested in the bone marrow tissue of 20 patients with lymphoma malignum. The patients were not treated. There was no neoplastic infiltration in their bone marrows. The concentrations of magnesium, manganese, zinc, copper and ferrum were determined by the spectrophotometric method using atomic absorption spectrophotometer (Pye Unicam SP-192). The level of elements was compared to the value of blood morphology. The small value of MCV (mean corpuscular volume) was accompanied by a low level of copper, zinc and manganese although the values of MCH (mean corpuscular hemoglobin) and MCHC (mean corpuscular hemoglobin concentration) were normal.