Comparative analysis of the spirographic and hemodynamic parameters in preoperative evaluation of patients with lung...

Surgery is the recommended treatment for nonmicrocellular lung cancer. The spirometric tests completed with gasometric systemic blood analysis and electrocardiographic investigation are the standard in the evaluation for tolerance of lung tissue resection. The catheterization of the right heart is used to assess circulatory systems efficiency in patients qualified for pulmonary tissue resection. The purpose of the study was to evaluate the correlations between basic spirographic and hemodynamic parameters measured at rest and after exercise. The studied population consisted of 50 consecutive male patients 21 to 72 years old with bronchial carcinoma, considered to be candidates for lung tissue resection. The vital capacity, and one-second forced expiratory volume were obtained. The hemodynamic examination was performed using Swan-Ganz thermodilution catheter. The systolic, diastolic and medium central venous pressure, pulmonary artery pressure and pulmonary wedge pressure were measured. Gasometric examination for peripheral arterial and mixed venous blood was performed--pH, PO2, PaCO2, SaO2. The results were subject to statistical analysis. The correlation between spirographic indicators and hemodynamic parameters were studied. Statistical analysis revealed high level of correlation between the average blood pressure in pulmonary artery, both at rest and after exercise, and ratio of one-second forced expiratory volume related to current vital capacity. The revealed correlations allow to solve regression equations making in possible to calculate likely values of the average blood pressure in pulmonary artery on the basis of spirographic values.