Related Experiment Video
Updated: Sep 20, 2026

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT)
Published on: January 7, 2018
Insulin resistance, parameters of carbohydrate metabolism, anthropometric parameters, interactions in diabetic
Wojciech Szydłowski1, Jerzy Łopatyński
1Primary Health Care Department of Family Medicine Department, Medical University of Lublin.
Abstract:
The aim of the study was to investigate relationships between insulin resistance index and basic parameters of carbohydrate metabolism and anthropometric values. We investigated patients with diabetes mellitus t.2 (n = 36) treated with oral hypoglycemic agents. The control group represented patients with normal glucose tolerance (n = 37). Both, the group with diabetes and control had similar values of anthropometric parameters. The insulin resistance index showed significant correlations with fasting plasma insulin and glucose concentrations and HbA1C level in both groups. In the group with normal glucose tolerance we showed significant correlations between insulin resistance index and anthropometric parameters (waist circumference, BMI, body weight, WHR). We did not find any significant relationships between insulin resistance and anthropometric parameters in the diabetic group.
Related Concept Videos
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in the...
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Type II Diabetes II: Pathophysiology
Type II Diabetes I: Introduction
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Oral Hypoglycemic Agents: Biguanides and Glitazones
