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Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

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Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
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Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

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Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
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Myocarditis I: Introduction01:21

Myocarditis I: Introduction

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Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
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Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

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Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
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Improved Rodent Model of Myocardial Ischemia and Reperfusion Injury
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Endomyocardial fibrosis in China.

R Yin1

  • 1Institute of Cardiovascular Diseases, Guangxi Medical University, Nanning 530021.

Chinese Medical Sciences Journal = Chung-Kuo I Hsueh K'O Hsueh Tsa Chih
|August 6, 2003
PubMed
Summary

Endomyocardial fibrosis (EMF) in China presents with pathological and clinical features similar to tropical regions, predominantly affecting the right ventricle. Etiology and epidemiology remain unknown, requiring further investigation.

Area of Science:

  • Cardiology
  • Pathology
  • Epidemiology

Background:

  • Endomyocardial fibrosis (EMF) is a rare cardiac condition.
  • Understanding its characteristics in diverse geographical regions is crucial.

Purpose of the Study:

  • To detail the epidemiological, pathological, and clinical features of EMF in China.
  • To review diagnostic and therapeutic experiences with EMF in China.

Main Methods:

  • Literature search of Chinese-language publications from 1965 to 1997.
  • Inclusion of studies on EMF and restrictive cardiomyopathy.

Main Results:

  • Eighty-seven Chinese EMF cases were analyzed, predominantly in the south.
  • Right ventricular involvement was the most common presentation (12% pure RV, 48% combined).

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  • Diagnosis confirmed via autopsy, echocardiography, angiocardiography, and endomyocardial biopsy.
  • Conclusions:

    • EMF is diagnosed in China, with features resembling tropical forms but a higher prevalence of right ventricular involvement.
    • Etiology, incidence, and epidemiology of EMF in China are yet to be determined.