Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Development of the Dutch Johne's disease control program supported by a simulation model.

Huybert Groenendaal1, Mirjam Nielen, Jan Willem Hesselink

  • 1Department of Farm Management, Wageningen University, P.O. Box 9101, 6700 HB Wageningen, The Netherlands. huybert.groenendaal.wg03@wharton.upenn.edu

Preventive Veterinary Medicine
|August 6, 2003
PubMed
Summary

A simulation model indicated that traditional test-and-cull strategies are ineffective for controlling Johne's disease. Improved calf management and hygiene, as implemented in the Paratuberculosis Program Netherlands (PPN), offer a more effective and economical solution for dairy farms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum to "Preclinical safety assessment of holmium-based microspheres for micro-brachytherapy in mice" [European Journal of Pharmaceutical Sciences 217 (2026) 107419].

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·2026
Same author

Preclinical safety assessment of holmium-based microspheres for micro-brachytherapy in mice.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·2025
Same author

Equine veterinarians' care priorities regarding vaccination, colic, lameness and pre-purchase scenarios.

Equine veterinary journal·2025
Same author

Economic costs of liver abscesses in U.S. beef feedlot cattle: a comprehensive economic analysis.

Journal of animal science·2025
Same author

Network meta-analysis based ranking of dry off interventions to cure or prevent intramammary infections in dairy cows.

Preventive veterinary medicine·2025
Same author

Quantitative CT imaging and radiation-absorbed dose estimations of <sup>166</sup>Ho microspheres: paving the way for clinical application.

European radiology experimental·2024

Area of Science:

  • Veterinary Epidemiology
  • Disease Modeling
  • Animal Health Economics

Background:

  • Johne's disease (paratuberculosis) poses a significant challenge to cattle health and farm economics.
  • Previous control strategies in The Netherlands primarily focused on test-and-cull methods.
  • The need for effective and economically viable national control programs was identified.

Purpose of the Study:

  • To develop and utilize a simulation model (JohneSSim) for designing a national Johne's disease control program.
  • To evaluate the efficacy and economic feasibility of various control strategies.
  • To inform the development of a new national control program for dairy farms.

Main Methods:

  • Development of the JohneSSim simulation model to predict disease dynamics.

Related Experiment Videos

  • Simulation of compulsory test-and-cull strategies.
  • Evaluation of improved calf management and hygiene strategies.
  • Adaptation of the model for beef cow herds and analysis of specific strategies like calf-adult separation.

    • Main Results:

    • Test-and-cull strategies were found to be insufficient for eradication within 20 years and economically unattractive.
    • Improved calf management showed greater potential for prevalence reduction.
    • An "ideal test" strategy was effective but economically unviable due to high culling rates.
    • Control strategies were largely ineffective for beef cow herds, with calf-adult separation being impractical.
    • The simulation supported the development of the Paratuberculosis Program Netherlands (PPN) for dairy farms.

    Conclusions:

    • Traditional test-and-cull methods are not sufficient for Johne's disease eradication in The Netherlands.
    • Improved calf hygiene and management, as implemented in the PPN, are more effective and economically viable for dairy farms.
    • The PPN, based on stepwise improvements in calf hygiene, offers a promising approach to reducing Johne's disease prevalence.