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Emerging therapeutic strategies for myelodysplastic syndrome
John Barrett1, Minoo Battiwalla
1Stem Cell Allotransplantation Section, Hematology Branch, NHLBI, NIH, Building 10, Room 7C103, 9000 Rockville Pike, Bethesda, MD 20892, USA. barrettj@nih.gov
Current Hematology Reports
|August 7, 2003
Abstract:
Increasing understanding of the pathophysiology of myelodysplastic syndromes (MDS) and a greater appreciation of the large impact that marrow failure has on the symptomatology and outcome of MDS have led to new treatment approaches. We describe recent developments of methods to manage marrow failure, suppress the MDS clone, and widen the applicability of curative treatment with allogeneic stem cell transplants.