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Updated: Sep 20, 2026
Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
Second-trimester sonographic diagnosis of diastrophic dysplasia: report of 2 index cases
Joseph R Wax1, Molly Carpenter, Wendy Smith
1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, Maine, USA. waxj@mmc.org
Objective:
To describe the sonographic features of diastrophic dysplasia in 2 second-trimester index offspring.
Methods:
Real-time sonography was performed on 2 second-trimester fetuses with no risk factors for skeletal dysplasia.
Results:
Each fetus had severe bilateral upper and lower extremity long bone shortening, hitchhiker thumbs and great toes, and clubbed feet, indicating a diagnosis of diastrophic dysplasia.
Conclusions:
Index cases of diastrophic dysplasia may be correctly diagnosed on the basis of second-trimester sonography.
