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MMR and autism: moving from controversy toward consensus
1Vaccine Education Center, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, PA 19104, USA. coffin@E-mail.chop.edu
Abstract:
As controversy swirls around the putative association between the measles-mumps-rubella vaccine and autism, the methods of scientific investigation, established more than 150 years ago, bear remembering. In this article, we will discuss the origins of this hypothesis, evidence in support of and at variance with this theory and future investigations that may help to resolve this debate.
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These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.

