[Morphometric analysis of the vascular tree of fetal tubular bones in an experimental model]

The area of interest for the longitudinal growth is the distal growth plate. In a postmortem study we were interested in changes of the epiphyseal vascular length density after fracture and surgical therapy of foetal and neonatal femora (25th to 40th post conceptional weeks). We formed three groups of equal size. Group A (25 femora) was the control group. In group B and C we performed fractures in the middle third of the femora, in group C the femora was operated with a plate afterwards. A microangiography of all femora occurred and after plastination transparent slices were produced. In this manner we could study the epiphyseal vessels in the growth plate. Using image analyses we could show that vascular density of the epiphyseal growth plate could be verified only through fracture but not by surgical therapy. The integrity of the distal epiphyseal vascular architecture is the aim after all.