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[Expression of E-cadherin in human embryo]
1Department of Gynecology and Obstetrics, Fuzhou General Hospital, Fuzhou, Fujian, 350025 PR China. liuyun95@sina.com
Objective:
To investigate the role of calcium dependent adhesion molecules (cadherin) during the implantation and development of human embryo by studying the expression of E-cadherin in human embryo and blastocysts.
Methods:
Expression of E-cadherin in preimplantation embryos and blastocysts was detected by indirect immunofluorescence assay and quantitated by laser scanning confocal microscopy.
Results:
Expression of E-cadherin was found in all the preimplantation embryos and blastocysts the present authors studied. The expression was higher in blastocysts than that in preimplantation embryos.
Conclusion:
The above results suggested that human embryos and blastocysts could express E-cadherin and the expression increased during their development. These may be of significance to the adhesion and implantation of the human embryo and blastocysts.
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