[Primary approach on midgastric-transverse band modifying the distribution of food between proximal and distal...

To explore the physiological function of the midgastric-transverse band (MTB) in the modification of intragastric food distribution in digestive period.

18 healthy subjects(HS) and 18 patients with functional dyspepsia(FD) participated in this study. After fasting over 8 hours all subjects took 150 ml of milk (777 J) mixed with 150 g Magnesium Sulfate, and laid supinely on 30 degrees angle with horizontal line, X-ray films were taken at 0, 30, 60, and 90 minutes after the meal, respectively. Analyzed parameters included the width of MTB, the total, proximal and distal gastric area (TGA, PGA and DGA), the ratio of proximal and distal stomach during every 30 minutes period, the correlation between MTB and PGA, MTB and DGA.

(1) There was significant difference of MTB and DGA in every period postprandially (P < 0.05 or 0.01), by contrast, there were no significant differences of TGA or PGA between HS and FD except at TGA 90 min (P < 0.05). (2) There were close correlation between MTB and PGA at 0 (P < 0.01), 30 (P < 0.01), 60 min (P < 0.01) after the meal in HS, but only at 0 min (P < 0.01) in FD. Also close correlations between MTB and DGA at 60 (P < 0.01) and 90 min (P < 0.01) in HS, but in FD. (3) the ratios of PGA from 0-30 min and 60-90 min in FD significantly decreased respectively, however the other ratios were shown no significant difference between HS and FD during each period. (4) there were close correlations between PGA and MTB at 0, 30, 60 min after the meal in HS, however except 0 min there were no correlations in FD. By contrast, between DGA and MTB there were close correlations at 60, or 90 min in HS, no correlation in FD at any time point.

MTB may play an important role in modifying intragastric food distribution in HS, while the dysfunction of MTB may result in the distal gastric overloading in FD, the mechanism of MTB needs further studies.