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Updated: Sep 20, 2026
Application of Hemostatic Devices in Laparoscopic Hepatectomy
Published on: April 19, 2022
[Diagnosis and management of gestational trophoblastic tumor with liver metastases]
1Department of Obstetrics and Gynecology, PUMC Hospital, CAMS, PUMC, Beijing 100730, China. xiangy@pumch.csc.ac.cn
Objective:
To evaluate management options and clinical prognosis for women presenting gestational trophoblastic tumor (GTT) with liver metastases.
Methods:
We retrospectively analyzed sixteen GTT patients with liver metastases treated in the Peking Union Medical College (PUMC) hospital from 1985 to 1998. All were treated with 5-FU combined chemotherapy or EMA/CO regimen. Eight of them received hepatic artery infusion chemotherapy. Treatment outcome was measured by beta subunit human chorionic gonadotropin assay (beta-hCG) and by imaging studies which included ultrasound and computerized tomography.
Results:
Of 16 cases, 4 achieved complete remission; biochemical remission was obtained in 2 patients who were alive with residual tumor; 10 patients died of the disease. The overall survival rate was 37.5% (6/16).
Conclusions:
The outcome for women presenting with liver metastases from GTT is poor. Early diagnosis and prompt initiation with vigorous multi-agent chemotherapy given through multi-routes are emphasized for improving the treatment outcome.
