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Finding a place for immunonutrition.

William Alvarez1, Sohrab Mobarhan

  • 1Division of Gastroenterology, Hepatology and Nutrition, Loyola University Medical Center, Maywood, IL 60153, USA.

Nutrition Reviews
|August 9, 2003
PubMed
Summary
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Perioperative immunonutrition, using specific nutrients, reduced infectious complications and hospital stays in gastrointestinal cancer patients undergoing surgery. This nutritional support shows significant clinical benefits.

Area of Science:

  • Immunonutrition research explores pharmacologic effects of nutrients on immune and inflammatory responses.

Background:

  • Nutritional support is crucial for surgical patients, particularly those with gastrointestinal cancer.
  • The field of immunonutrition has gained traction over the past two decades.

Purpose of the Study:

  • To review the role of individual immunonutrients and clinical trials of nutrient combinations.
  • To assess the impact of perioperative immunonutrition in gastrointestinal cancer patients.

Main Methods:

  • A study administered a combination of immunonutrients perioperatively.
  • The study population comprised well-nourished gastrointestinal cancer patients undergoing elective surgery.
  • Outcomes were compared between patients receiving immunonutrients and those receiving no nutritional support.

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Main Results:

  • Patients receiving immunonutrients experienced a decreased rate of infectious complications.
  • The length of hospital stay was reduced in the immunonutrient group.
  • These findings suggest a beneficial effect of perioperative immunonutrition.

Conclusions:

  • Perioperative immunonutrition can decrease infectious complications and hospital stay in surgical gastrointestinal cancer patients.
  • Further review of individual components and clinical trials supports the use of immunonutrition.