Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Disorders of the Male Reproductive System

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reply to Francesco Montorsi, Edoardo Pozzi, Marco Bianchi, et al's Letter to the Editor re: Gautier Müllhaupt, Lukas Hechelhammer, Nicole Graf, et al. Prostatic Artery Embolisation Versus Transurethral Resection of the Prostate for Benign Prostatic Obstruction: 5-year Outcomes of a Randomised, Open-label, Noninferiority Trial. Eur Urol Focus 2024;10:788-95.

European urology focus·2025

Same author

Bounce effect or local recurrence after low-dose-rate brachytherapy of the prostate? When prostate-specific membrane antigen positron emission tomography-computed tomography is false positive: a case report.

Journal of medical case reports·2025

Same author

PSMA PET/CT in biochemical recurrence of prostate cancer with PSA levels ≤ 0.2 ng/mL: a German multicenter analysis of conventional PSMA tracers, including [<sup>68</sup>Ga]Ga-PSMA-11, [<sup>68</sup>Ga]Ga-PSMA I&T, and [<sup>18</sup>F]PSMA-1007.

European journal of nuclear medicine and molecular imaging·2025

Same author

Personalized Dynamic Prediction Model for Biopsy Timing in Patients With Prostate Cancer During Active Surveillance.

JAMA network open·2025

Same author

Predicting Urinary Function Outcomes Following Low-dose-rate Brachytherapy for Prostate Cancer.

European urology open science·2024

Same author

High interobserver variability of PTEN immunohistochemistry defining PTEN status in low- to intermediate-risk prostate cancer: results of the first German ring trial.

Virchows Archiv : an international journal of pathology·2024

Search research articles

Related Experiment Video

Updated: May 11, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

Problems with prostate-specific antigen screening: a critical review.

Hans-Peter Schmid¹, Ladislav Prikler, Axel Semjonow

¹Department of Urology, Kantonsspital, 9007 St. Gallen, Switzerland.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer

|August 9, 2003

Summary

This summary is machine-generated.

The impact of prostate cancer population screening on mortality and quality of life remains unclear. Ongoing international trials aim to clarify these effects, while opportunistic screening is advised for men with a 10-year life expectancy.

More Related Videos

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization

Published on: November 17, 2023

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

Related Experiment Videos

Last Updated: May 11, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization

Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization

Published on: November 17, 2023

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

Area of Science:

Urology
Public Health
Oncology

Background:

The effectiveness of population-wide prostate cancer screening in reducing mortality and impacting quality of life is not definitively established.
Current evidence is insufficient to guide widespread screening protocols.

Purpose of the Study:

To evaluate the impact of population screening on prostate cancer-specific mortality.
To assess the effects of prostate cancer screening on patient quality of life.

Main Methods:

Prospective national and international studies are underway to gather data.
Key trials include those in Tyrol, Austria; Quebec City, Canada; the Prostate, Lung, Colorectal and Ovarian (PLCO) trial in the US; and the European Randomized Study of Screening for Prostate Cancer (ERSPC).

Main Results:

Data collection and analysis are ongoing across multiple large-scale prospective studies.
Definitive results regarding mortality reduction and quality of life changes are pending.

Conclusions:

The definitive impact of prostate cancer screening on mortality and quality of life requires further investigation through ongoing trials.
Opportunistic screening is currently recommended for men with a life expectancy of at least 10 years.