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[Star anise poisoning in infants]
P Minodier1, P Pommier, E Moulène
1Urgences pédiatriques, CHU Nord, chemin des Bourrelly, 13915 Marseille cedex 20, France. philippe.minodier@ap-hm.fr
Summary
Star anise herbal tea can cause neurological issues in infants, including tremors and vomiting. This poisoning risk is linked to potential contamination with Japanese star anise, a known neurotoxin.
Area of Science:
- Toxicology
- Herbal Medicine Safety
Background:
- Star anise (Illicium verum) is traditionally used for infant colic.
- Concerns exist regarding potential adverse neurological effects.
Observation:
- Two cases of star anise poisoning in infants under six months are reported.
- Infants presented with tremors, spasms, hypertonia, crying, nystagmus, and vomiting.
- Japanese star anise (Illicium religiosum) contamination was identified in one case.
Findings:
- Japanese star anise contains neurotoxic sesquiterpenic lactones.
- Confusion or adulteration between Chinese and Japanese star anise species can lead to poisoning.
- Infant exposure occurred via star anise herbal tea.
Implications:
- Accidental star anise poisoning in infants poses a significant neurotoxic risk.
- Regulatory measures, such as the 2001 prohibition in France, are crucial.
- Continued vigilance is needed due to potential availability in informal markets and self-importation.