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West Nile virus encephalitis during pregnancy
Jeff B Chapa1, Jennifer T Ahn, Laura M DiGiovanni
1Department of Obstetrics and Gynecology, University of Chicago, Chicago, Illinois, USA. jchapa@babies.bsd.uchicago.edu
Obstetrics and Gynecology
|August 9, 2003
Summary
West Nile virus can cause severe meningoencephalitis in pregnant women. Early diagnosis and supportive care are crucial for maternal recovery, with no apparent fetal harm observed in this case.
Area of Science:
- Neurology
- Infectious Diseases
- Maternal-Fetal Medicine
Background:
- West Nile virus (WNV) is an emerging infectious pathogen in the United States.
- While most WNV infections are asymptomatic, severe neuroinvasive disease, such as meningoencephalitis, can occur.
Observation:
- A case of West Nile virus meningoencephalitis during the second trimester of pregnancy is presented.
- The patient exhibited fever, nuchal rigidity, and altered mental status.
Findings:
- Diagnosis was confirmed by detecting West Nile virus immunoglobulin M antibodies in cerebrospinal fluid.
- The patient showed gradual clinical improvement with supportive care.
Implications:
- Healthcare providers should consider West Nile virus in pregnant women with neurological symptoms and fever, especially in endemic regions.
- This case highlights the importance of awareness for prompt diagnosis and management of WNV in pregnancy.