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Fetal brain tumors.

Sergio Cavalheiro1, Antonio Fernandes Moron, Wagner Hisaba

  • 1Section of Pediatric Neurosurgery, Federal University of São Paulo, Rua Botucatu 591/42, 04023-062 São Paulo, Brazil. iscava@uol.com.br

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|August 9, 2003
PubMed
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Fetal intracranial tumors are rare but increasingly diagnosed with antenatal ultrasound. Surgical intervention after birth can lead to positive outcomes, with most surviving infants showing normal development.

Area of Science:

  • Pediatric Neurosurgery
  • Fetal Medicine
  • Medical Imaging

Background:

  • Fetal intracranial tumors are uncommon conditions with historically poor prognoses.
  • Advances in antenatal ultrasound imaging have increased the diagnosis rate of these tumors.

Purpose of the Study:

  • To review the management and outcomes of fetal intracranial tumors diagnosed and treated between 1992 and 2002.
  • To evaluate the effectiveness of interventions for fetal intracranial tumors.

Main Methods:

  • Retrospective analysis of 18 cases of fetal intracranial tumors treated at tertiary care centers.
  • Inclusion of cases diagnosed via antenatal ultrasound and managed surgically postnatally.

Main Results:

  • Choroid plexus tumors and teratomas were the most common types.

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  • 11 cases presented with fetal hydrocephalus; 5 underwent repeated cephalocenteses.
  • 16 neonates underwent craniotomy, with 12 survivors (9 normal, 3 with developmental delays).
  • Conclusions:

    • Early diagnosis and timely surgical intervention for fetal intracranial tumors can improve survival rates.
    • While outcomes are generally positive, neurodevelopmental monitoring is crucial for affected infants.