Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Weight gain after lung transplantation.

Lianne G Singer1, Timothy R Brazelton, Ramona L Doyle

  • 1Division of Pulmonary and Critical Care Medicine, Stanford University School of Medicine, Stanford, California, USA. lianne.singer@uhn.on.ca

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
|August 12, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Approach to prevention and management of chronic lung allograft dysfunction in North American lung transplant centers.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

Latent Class Analysis Identifies Pulmonary Function Trajectory Phenotypes in Lung Transplant Recipients with Chronic Allograft Dysfunction.

medRxiv : the preprint server for health sciences·2026
Same author

Economic evaluation of ex-vivo lung perfusion for lung transplantation: A cost-utility analysis from a large Canadian center.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

Clinical implications of frailty in hospitalized patients with pulmonary arterial hypertension.

Chronic respiratory disease·2025
Same author

Development and validation of a bronchoalveolar lavage genomic classifier for acute cellular rejection.

EBioMedicine·2025
Same author

Reduced lung fluid club cell secretory protein informs chronic lung allograft dysfunction risk.

The European respiratory journal·2025

Weight gain after lung transplantation is common, with predictors like age and ventilation time identified. Higher weight gain in the first year is linked to improved survival outcomes.

Area of Science:

  • Pulmonology
  • Transplant Surgery
  • Clinical Research

Background:

  • Weight gain is a common post-lung transplant observation.
  • The extent, predictors, and impact of this weight gain remain unclear.

Purpose of the Study:

  • To determine the magnitude and predictors of weight gain within the first year after lung transplantation.
  • To investigate the association between first-year weight gain and long-term survival.

Main Methods:

  • Retrospective cohort study of 826 lung transplant recipients from 12 international centers.
  • Analysis of demographic and clinical factors predicting weight change using multiple linear regression.
  • Cox proportional hazards analysis to assess the relationship between weight gain and survival.

Related Experiment Videos

Main Results:

  • Median weight change was 10% in the first year post-transplant.
  • Predictors of weight gain included age, ventilation duration, disease type (obstructive, interstitial), and ischemic time.
  • Weight gain above the median was associated with improved survival (aHR 0.61), with infection as a more common cause of death versus malignancy in lower weight gain groups.

Conclusions:

  • Significant weight gain is a key event in the first year after lung transplantation.
  • Identifying predictors allows for targeted interventions in high-risk patients.
  • Greater weight gain correlates with enhanced subsequent survival.