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Body mass index and uterine receptivity in the oocyte donation model
Saranya Wattanakumtornkul1, Mark A Damario, Sharon A Stevens Hall
1Mayo Clinic, Rochester, Minnesota 55905, USA.
Objective:
To evaluate the relationship of body mass index (BMI) to uterine receptivity under conditions of programmed hormonal support and standardized embryo quality.
Design:
Retrospective cohort study.A tertiary referral center.
Patients:
Ninety-seven consecutive first-cycle recipients of anonymous oocyte donation. After programmed hormone replacement, recipients had transfer of embryos derived from oocyte donation. Anonymous oocyte donors received ovarian stimulation and underwent transvaginal ultrasound-guided oocyte retrieval.
Setting:
A receiver operator characteristic (ROC) curve of implantation versus BMI. Area under the ROC curve was 0.51, 95% confidence interval (CI) 0.41-0.62, suggesting no relationship between BMI and implantation. There was no difference in implantation rates between obese (BMI >or=30) and nonobese (BMI <30) recipients, odds ratio 1.1, 95% CI 0.5-2.4.
Conclusion(S):
Uterine receptivity was unimpaired in women with increased BMI when hormonal support and embryo quality were standardized.