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Published on: November 29, 2018
Normal range and variation of the zona pellucida-induced acrosome reaction in fertile men
De Yi Liu1, Tanya Stewart, H W Gordon Baker
1Department of Obstetrics and Gynaecology, University of Melbourne, Carlton, Victoria. dyl@unimelb.edu.au
Objective:
To investigate the normal range of the zona pellucida (ZP)-induced acrosome reaction (AR) in fertile men.
Design:
A study of normative data.
Setting:
Academic research and teaching tertiary hospital.None.Fertile men (n = 111) who had children or whose female partner was currently pregnant. MAIN OUTCOME MEASURE (S): Semen analysis, sperm-ZP binding, and the ZP-induced AR.
Result(S):
There was wide range for the ZP-induced AR: 20%-98% with a mean of 48%. The ZP-induced AR was significantly correlated with sperm concentration and normal morphology. The ZP-induced AR was significantly lower in men with sperm concentration
Conclusion(S):
There is a wide range of the ZP-induced AR in fertile men that is correlated with sperm concentration and normal morphology.
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