Related Experiment Video
Updated: Sep 20, 2026
Laparoscopic Oocyte Retrieval and Cryopreservation during Vaginoplasty for Treatment of Mayer-Rokitansky-Kuster-Hauser Syndrome
Published on: May 10, 2022
Effectiveness of autocrosslinked hyaluronic acid gel after laparoscopic myomectomy in infertile patients: a
Massimiliano Pellicano1, Silvia Bramante, Domenico Cirillo
1Department of Obstetrics and Gynecology, University of Naples "Federico II", Naples, Italy. pellican@unina.it
Objective:
To assess the efficacy of autocrosslinked hyaluronic gel in postsurgical adhesion prevention after laparoscopic myomectomy.
Design:
Prospective, randomized, controlled study.
Setting:
University of Naples "Federico II".Thirty-six infertile women with symptomatic myomas were randomly divided into two groups of 18 patients each.
Intervention(S):
Laparoscopic myomectomy with subserous sutures or interrupted figure 8 sutures, with (group A) or without (group B) application of autocrosslinked hyaluronic acid (HA) gel.
Main Outcome Measure(S):
Rate of postsurgical adhesions at 60-90 days of follow-up. The rate of subjects who developed postoperative adhesions was significantly lower in group A in comparison with group B (27.8% vs. 77.8%). In both groups, the rate of adhesions was significantly higher in patients treated with interrupted figure 8 sutures than with subserous sutures.
Conclusion(S):
Autocrosslinked HA gel is a promising resorbable agent barrier for the reduction of postoperative adhesions after laparoscopic myomectomy. Moreover, the type of suture is a factor influencing the postsurgical adhesion formation.
