Genetics of common obesity and type 2 diabetes: please forget diseases and study pathogenic traits

An AAVrh10-CAG-CYP21-HA vector allows persistent correction of 21-hydroxylase deficiency in a Cyp21-/- mouse model.

Gene therapy·2017

Association of environmental markers with childhood type 1 diabetes mellitus revealed by a long questionnaire on early life exposures and lifestyle in a case-control study.

BMC public health·2016

The P2 promoter of the IGF1 gene is a major epigenetic locus for GH responsiveness.

The pharmacogenomics journal·2015

Decrease in clinical hypoglycemia in young children with type 1 diabetes treated with free-mixed aspart and detemir insulin: an open labeled randomized trial.

Pediatric diabetes·2014

Effects of a controlled hypoglycaemia test on QTc in adolescents with Type 1 diabetes.

Diabetic medicine : a journal of the British Diabetic Association·2008

Effects of an early postnatal treatment of hypogonadotropic hypogonadism with a continuous subcutaneous infusion of recombinant follicle-stimulating hormone and luteinizing hormone.

The Journal of clinical endocrinology and metabolism·2008

Lower glucagon response and attenuated hepatic glucagon signaling in MASLD.

Diabetes & metabolism·2026

Comparative effectiveness of sodium-glucose cotransporter-2 versus dipeptidyl peptidase-4 inhibitors on all-cause mortality in type 2 diabetes: a multinational propensity score-matched cohort study.

Diabetes & metabolism·2026

Inpatient outcomes of diabetic ketoacidosis complicating pancreatic cancer: a national inpatient sample analysis.

Diabetes & metabolism·2026

Association between the glycemic risk index and peripheral atherosclerosis in hospitalized patients with type 2 diabetes: a cross-sectional study.

Diabetes & metabolism·2026

Glucagon-like peptide-1 receptor agonists and risk of pancreaticobiliary cancers in patients with type 2 diabetes: a nationwide cohort study.

Diabetes & metabolism·2026

Decreased risk of new-onset osteoporosis in patients with Type 2 diabetes on SGLT-2 inhibitors.

Diabetes & metabolism·2026

Evaluating the pathogenic significance of unique chromosomal variants in craniosynostosis using patient-derived induced pluripotent stem cells and mouse modelling.

Genetics in medicine : official journal of the American College of Medical Genetics·2026

[Genetic and functional characterization of a novel KIT splicing variant in a Chinese three-generation pedigree with piebaldism].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences·2026

Genome-wide association study of sarcopenia index reveals sex-stratified genetic architecture.

Biology of sex differences·2026

Whole-Exome Sequencing in a Consanguinity-Enriched South Indian Retinitis Pigmentosa Cohort: Diagnostic Yield and Molecular Spectrum.

Ophthalmology science·2026

Genetic analysis, reproductive decision-making, and pregnancy outcomes in 51 Chinese osteogenesis imperfecta families.

Journal of assisted reproduction and genetics·2026

Monoallelic loss-of-function variants in ZNF536 are associated with a neurodevelopmental disorder with prominent behavioral features.

American journal of human genetics·2026

Related Experiment Videos

Genetics of common obesity and type 2 diabetes: please forget diseases and study pathogenic traits

Related Concept Videos

An AAVrh10-CAG-CYP21-HA vector allows persistent correction of 21-hydroxylase deficiency in a Cyp21-/- mouse model.

Association of environmental markers with childhood type 1 diabetes mellitus revealed by a long questionnaire on early life exposures and lifestyle in a case-control study.

The P2 promoter of the IGF1 gene is a major epigenetic locus for GH responsiveness.

Decrease in clinical hypoglycemia in young children with type 1 diabetes treated with free-mixed aspart and detemir insulin: an open labeled randomized trial.

Effects of a controlled hypoglycaemia test on QTc in adolescents with Type 1 diabetes.

Effects of an early postnatal treatment of hypogonadotropic hypogonadism with a continuous subcutaneous infusion of recombinant follicle-stimulating hormone and luteinizing hormone.

Lower glucagon response and attenuated hepatic glucagon signaling in MASLD.

Comparative effectiveness of sodium-glucose cotransporter-2 versus dipeptidyl peptidase-4 inhibitors on all-cause mortality in type 2 diabetes: a multinational propensity score-matched cohort study.

Inpatient outcomes of diabetic ketoacidosis complicating pancreatic cancer: a national inpatient sample analysis.

Association between the glycemic risk index and peripheral atherosclerosis in hospitalized patients with type 2 diabetes: a cross-sectional study.

Glucagon-like peptide-1 receptor agonists and risk of pancreaticobiliary cancers in patients with type 2 diabetes: a nationwide cohort study.

Decreased risk of new-onset osteoporosis in patients with Type 2 diabetes on SGLT-2 inhibitors.

Evaluating the pathogenic significance of unique chromosomal variants in craniosynostosis using patient-derived induced pluripotent stem cells and mouse modelling.

[Genetic and functional characterization of a novel KIT splicing variant in a Chinese three-generation pedigree with piebaldism].

Genome-wide association study of sarcopenia index reveals sex-stratified genetic architecture.

Whole-Exome Sequencing in a Consanguinity-Enriched South Indian Retinitis Pigmentosa Cohort: Diagnostic Yield and Molecular Spectrum.

Genetic analysis, reproductive decision-making, and pregnancy outcomes in 51 Chinese osteogenesis imperfecta families.

Monoallelic loss-of-function variants in ZNF536 are associated with a neurodevelopmental disorder with prominent behavioral features.

Related Experiment Videos

Genetics of common obesity and type 2 diabetes: please forget diseases and study pathogenic traits

Related Concept Videos

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