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Updated: Aug 4, 2026

Neuropharmacological Manipulation of Restrained and Free-flying Honey Bees, Apis mellifera
Published on: November 26, 2016
Central non-NMDA receptors of a honey bee with hereditary kynurenine deficiency
N G Lopatina1, I V Ryzhova, E G Chesnokova
1Laboratory of Higher Nervous Activity Genetics, Russian Academy of Sciences, St. Petersburg.
Abstract:
Pharmacological characteristics of non-NMDA receptors involved in associative learning were studied in wild honey bees (normal) and carriers of snow laranja mutation (kynurenine deficiency) by pharmacological analysis and behavioral criteria. The effects of systemic injections of non-NMDA receptor agonists (AMPA, kainic, quisqualic, and domoic acids), AMPA receptor antagonist (NS257-HCl), and AMPA receptor modulator (cyclothiaside) on retention of conditioned reflexes in short-term memory (1 min after the end of learning) were studied. The pharmacological characteristics of non-NMDA receptors were changed in snow laranja mutants with kynurenine deficiency.
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