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Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
12:00

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model

Published on: November 24, 2014

[Off-pump coronary artery bypass grafting; its impact on renal function]

H Yaku1, T Okano, Y Shimada

  • 1Department of Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|August 13, 2003
PubMed

Insights

Off-pump coronary artery bypass grafting (OPCAB) preserves renal function compared to on-pump surgery. This study found similar rates of renal impairment but a lower postoperative to preoperative creatinine ratio in the OPCAB group.

Area of Science:

  • Cardiovascular Surgery
  • Nephrology
  • Perioperative Medicine

Background:

  • Coronary artery bypass grafting (CABG) is a common cardiac procedure.
  • Maintaining renal function during CABG is crucial for patient outcomes.
  • Off-pump CABG (OPCAB) aims to reduce complications associated with cardiopulmonary bypass.

Purpose of the Study:

  • To evaluate the impact of off-pump CABG (OPCAB) on perioperative renal function.
  • To compare renal function between OPCAB and conventional on-pump CABG procedures.

Main Methods:

  • A retrospective study of 350 patients undergoing isolated CABG between January 1999 and September 2002.
  • Patients were divided into two groups: OPCAB (n=214) and on-pump CABG (n=136).
  • Perioperative serum creatinine (CRE) levels were analyzed and compared between the groups.

Main Results:

  • The incidence of renal impairment (CRE > 1.5 mg/dl) was similar between the OPCAB (8%) and on-pump (4%) groups.
  • Postoperative renal impairment rates were comparable: 20% in OPCAB versus 18% in the on-pump group.
  • The ratio of postoperative to preoperative CRE was significantly lower in the OPCAB group (1.28) compared to the on-pump group (1.44).

Conclusions:

  • Off-pump CABG (OPCAB) demonstrates a trend towards better preservation of renal function compared to on-pump CABG.
  • While not reaching statistical significance in all measures, the lower CRE ratio suggests improved renal recovery with OPCAB.
  • OPCAB may be a favorable option for patients concerned about perioperative renal function.
Abstract

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