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A genome wide scan for early onset primary hypertension in Scandinavians
Fredrik von Wowern1, Kristina Bengtsson, Cecilia M Lindgren
1Department of Endocrinology, Malmö University Hospital, SE-205 02, Malmö, Sweden.
Human Molecular Genetics
|August 13, 2003
Abstract:
With the aim of identifying hypertension susceptibility loci, we performed a genome wide scan in Scandinavian sib-pairs with early onset primary hypertension. To be classified as affected, a diagnosis of primary hypertension at age /= 1.0) were fine mapped with additional markers. Multipoint non-parametric linkage analysis was performed using GENEHUNTER v 2.0. Using simulations, a nominal P