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Prolonged treatment for acute symptomatic refractory status epilepticus: outcome in children
Mustafa Sahin1, Caroline C Menache, Gregory L Holmes
1Division of Epilepsy and Clinical Neurophysiology and the Critical Care Neurology Service, Department of Neurology, Children's Hospital, Boston, MA 02115, USA.
Neurology
|August 13, 2003
Abstract:
High-dose suppressive therapy (HDST) is used to treat refractory status epilepticus (RSE). Prolonged therapy is required in some cases, and prognosis is important in making therapeutic decisions. The authors therefore studied the long-term outcome in previously normal children who survived prolonged HDST for acute symptomatic RSE. All have intractable epilepsy, and none returned to baseline.