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Multinucleation of the sodC-deficient Dictyostelium discoideum
Atsushi Tsuji1, Yuya Akaza, Shogo Nakamura
1Division of Bioengineering, Faculty of Engineering, Toyama University, Toyama, Japan.
Biological & Pharmaceutical Bulletin
|August 13, 2003
Abstract:
The cellular slime mold Dictyostelium discoideum expresses three genes (sodA, sodB and sodC) encoding the extracellular Cu/Zn superoxide dismutases. Following H(2)O(2) treatment, the expression of sodA and sodB increased while that of sodC decreased. The sodC null strain formed multinucleate cells in a shaking culture. These results suggest that sodC plays a unique role in Dictyostelium discoideum.