Related Experiment Video
Updated: Sep 20, 2026
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
Combined treatments in gastric cancer: radiotherapy
Vincenzo Valentini1, Francesco Cellini, Rolando M D'Angelillo
1Cattedra Radioterapia, Istituto di Radiologia, Policlinico Università A Gemelli Università Cattolica S Cuore, Largo F Vito 1, 00168 Roma, Italy. vvalentini@rm.unicatt.it
Abstract:
In the past decades radiation oncologists have not had a major interest in the treatment of gastric cancer. The concern on major toxicity related to an extended irradiation of the upper abdomen limited the experience in the treatment of this disease; therefore few data were available to evaluate any advantage of the use of radiation therapy. The results of the Gastrointestinal Intergroup Study promoted a new interest in the irradiation of gastric cancer. The analysis of the outcomes of the Intergroup Study supported the role of locoregional control in promoting better survival for patients treated with adjuvant chemoradiation vs resected patients (81% vs 71%). The studies reported in the last years on the use of radiotherapy in gastric carcinoma are reviewed.
Related Concept Videos
02:49Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
02:57Targeted Cancer Therapies
There are several types of targeted therapies against specific...
02:50Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...