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Updated: Sep 20, 2026

High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy
Published on: October 9, 2020
Application of amplitude-modulated radiofrequency fields to the magic-angle spinning NMR of spin-7/2 nuclei
P K Madhu1, Ole G Johannessen, Kevin J Pike
1Department of Chemistry, University of Southampton, Southampton SO17 1BJ, UK.
Abstract:
We report pulse sequences for the sensitivity enhancement of magic-angle spinning and multiple-quantum magic-angle spinning spectra of spin-72 systems. Sensitivity enhancement is obtained with the use of fast amplitude-modulated (FAM) radiofrequency pulses. In one-dimensional magic-angle spinning experiments, signal enhancement of 3 is obtained by a FAM pulse followed by a soft 90 degrees pulse. In two-dimensional multiple-quantum magic-angle spinning experiments, FAM pulses are used for both the excitation of multiple-quantum coherences and for their conversion into observable single-quantum coherences. The observed signal enhancements are 2.2 in 3Q experiments, 3.1 in 5Q experiments, and 4.1 in 7Q experiments, compared to the conventional two-pulse scheme. The pulse schemes are demonstrated on the 45Sc NMR of Sc2(SO4)3 x 5H2O and the 139La NMR of LaAlO3. We also demonstrate the generation of FAM pulses by double-frequency irradiation.
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