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Related Experiment Videos

Crohn's disease and cheilitis.

Abdulrahman A Al-Hussaini1, Helen M Machida, J Decker Butzner

  • 1Department of Pediatrics, Alberta Children's Hospital, Calgary, Canada.

Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie
|August 14, 2003
PubMed
Summary

This case report highlights an unusual presentation of Crohn's disease in a child, where recurrent lip swelling (cheilitis) preceded significant intestinal symptoms. Physicians should consider Crohn's disease in pediatric patients with persistent cheilitis.

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Area of Science:

  • Pediatric Gastroenterology
  • Immunology
  • Dermatology

Background:

  • Crohn's disease is a chronic inflammatory bowel disease.
  • Its presentation can be variable, especially in pediatric cases.
  • Extraintestinal manifestations are common but can precede gastrointestinal symptoms.

Observation:

  • A five-year-old boy presented with painless bilateral lip swelling.
  • He later developed abdominal pain, diarrhea, weight loss, and joint pain.
  • Colonoscopy revealed findings consistent with Crohn's colitis.

Findings:

  • The patient experienced relapsing cheilitis, particularly when steroid treatment for Crohn's disease was tapered.
  • Intestinal symptoms of Crohn's disease were minimal during these relapses.

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  • Colonic biopsies confirmed chronic inflammation, cryptitis, and fissure formation.

    • Implications:

    • This case underscores the importance of recognizing cheilitis as a potential early or isolated manifestation of pediatric Crohn's disease.
    • Physicians should maintain a high index of suspicion for inflammatory bowel disease in children with recurrent or persistent cheilitis.
    • Prompt diagnosis and management of Crohn's disease, even with atypical presentations, are crucial for long-term patient outcomes.