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[Platelet membrane Ca(2+) and Na(+), K(+)-ATPase activity and aggregation in myelodysplastic syndrome]
I V Bielins'ka1, H V Ostrovs'ka, V K Rybal'chenko
1Taras Shevchenko Kyiv National University, Ukraine.
Ukrains'Kyi Biokhimichnyi Zhurnal (1999 )
|August 15, 2003
Abstract:
Platelet aggregation was decreased under action of ADP and collagen in patients with myelodysplastic syndrome. The decrease in aggregation started from 3-rd minutes and decreased in 4 and 5 minutes after action of ADP. The study of Ca(2+)-ATPase and Na+, K(+)-ATPase membrane activities showed the decrease in Ca(2+)-ATPase and increase in Na+, K(+)-ATPase activity in the patients with myelodysplastic syndrome.