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Updated: Oct 13, 2026

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Published on: January 7, 2018
The fetal origins of adult hypertension
1MRC Environmental Epidemiology Unit, Southampton General Hospital, UK.
Aim:
To elucidate the fetal origins of hypertension.
Methods:
A systematic search was made for records of early growth, comprising measurements taken either at birth and/or during infancy, for groups of men and women now in middle-late life. Over 25,000 men and women born before 1931 were successfully traced.
Results:
Retarded growth in fetal life was strongly related to high blood pressure in adult life.
Conclusion:
Hypertension is programmed by an adverse environment in utero. It is linked to impaired development in both early and late gestation.
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