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Updated: Sep 20, 2026

Analyzing Tumor and Tissue Distribution of Target Antigen Specific Therapeutic Antibody
Published on: May 16, 2020
Studies on the large scale synthesis and anti-tumor activity of YSL
Chao Wang1, Wenfeng Ding, Ming Zhao
1College of Pharmaceutical Sciences, Peking University, Beijing, P.R. China.
Abstract:
H-Tyr-Ser-Leu-OH (YSL), isolated from the degradation products of porcine spleen, was synthesized by a solution method on a large scale via two synthetic strategies. Its structure was confirmed by spectroscopic and related analyses. The in vivo anti-tumor activity was evaluated with murine H22 tumor models. The result indicated that, with the administration of YSL, the survival time of the murine H22 implanted mice was significantly prolonged.
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