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Palladium-catalyzed intermolecular alpha-arylation of N-protected 2-piperidinones
Janine Cossy1, Arnault De Filippis, Domingo Gomez Pardo
1Laboratoire de Chimie Organique associé au CNRS, ESPCI, 10 rue Vauquelin, 75231 Paris Cedex 05, France. janine.cossy@espci.fr
Organic Letters
|August 15, 2003
Abstract:
[reaction: see text] The alpha-arylation of the zinc enolate of N-protected 2-piperidinones with aryl bromides in the presence of a palladium catalyst is described as a general method.