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Updated: Aug 7, 2026

The Use of Primary Human Fibroblasts for Monitoring Mitochondrial Phenotypes in the Field of Parkinson's Disease
Published on: October 3, 2012
Meeting summary--cell biology of Parkinson's disease and related neurodegenerative disorders
John Q Trojanowski1, Virginia M-Y Lee
1Center for Neurodegenerative Disease Research, Institute on Aging and Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. trojanow@mail.med.upenn.edu
Abstract:
Parkinsonian disorders (idiopathic Parkinson's disease and clinically similar disorders) are characterized by impaired movements caused by the degeneration of brain centers involved in regulating normal and smooth movements of the body and its extremities. The mechanisms that cause such degeneration are unknown. This Perspective summarizes research described at a meeting held in June 2003, which was organized by the National Institute of Neurological Disorders and Stroke and the National Institute on Aging to provide an update on recent advances in the cell biology of parkinsonian disorders.
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