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[The enteral feeding during the treatment of appendicular peritonitis in children]
Insights
Early enteral therapy (EET) significantly improved recovery for children with appendicular peritonitis and intestinal insufficiency syndrome (IIS). EET accelerated gut function restoration, reduced complications by half, and shortened hospital stays by 8 days.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Critical Care Medicine
Context:
- Appendicular peritonitis in children can lead to intestinal insufficiency syndrome (IIS).
- Standard postoperative care includes antibacterial, metabolic, and infusive therapies.
- Parenteral nutrition is often necessary for extended periods.
Purpose:
- To evaluate the efficacy of early enteral therapy (EET) in managing stage 2 intestinal insufficiency syndrome (IIS) in pediatric patients with appendicular peritonitis.
- To compare outcomes between patients receiving EET and those receiving standard postoperative care.
Summary:
- A study involving 65 pediatric patients (3-14 years) with appendicular peritonitis and IIS stage 2 compared early enteral therapy (EET) with standard care.
- EET involved a phased introduction of nutrient solutions, starting with glutamine-enriched solutions and progressing to more complex mixtures.
- The EET group showed faster recovery of intestinal peristalsis, reduced duration of infusive therapy and parenteral feeding, and a 2-fold decrease in postoperative complications.
Impact:
- EET accelerates the recovery of gastrointestinal tract functions in pediatric patients with IIS.
- This method reduces the incidence of postoperative complications and shortens hospital stays by an average of 8 days.
- EET is a pathophysiologically sound treatment, offering significant benefits over standard care for this patient population.
Abstract:
A total of 65 patients, aged 3 to 14, with different forms of appendicular peritonitis, in whom the intestinal insufficiency syndrome (IIS), stage 2, was diagnosed, were investigated. 35 patients were in the main group, and 30 patients were in the control group; the subjects of the latter group had a similar form of peritonitis, i.e. IIS, stage 2, it was confirmed clinically and by ultrasound examinations. The laparoscopic operations were carried out in all patients. The patients of both groups received postoperatively a similar therapy, i.e. the antibacterial, metabolic and infusive ones, as well as vitamins and parenteral feeding (daily caloric values--50-120 kcal/kg, protein--2-3 g/kg/day) according to a child's age and a clinical course of peritonitis. All children of the main group received postoperatively an early enteral therapy (EET), which involved 4 stages. Stage 1: introduction of the salt solution with added glutamine through the naso-gastric probe by increasing volumes and with respect to an individual tolerability of a patient; stage 2: introduction of semi-element mixtures; stage 3: introduction of 10% solutions of polymer balanced mixture; stage 4: introduction of 20% solutions of polymer mixtures. Ultrasound scanning and clinical methods were used to assess the efficiency of the recovery of intestinal peristalsis. The conducted investigations showed that the mean duration of the gastric-type EET amounted to 3-4 days, and the IIS was, on the average, arrested by days 6 or 7. The duration of infusive therapy and parenteral feeding went down, in the main group, by 2 days. A trend towards an increase of the erythrocyte level was noted in these patients. No differences were registered in the values of concentrations of total protein and albumin in the blood serum of patients in both groups from the 1st to 7th postoperative days, however, the infusions of plasma and albumin were made by 2 times more often in the main group as compared to the control one. The EET technique preserved the gastric mucous tunic intact, which cut the postoperative complications 2-fold, and consequently, it reduced the stay of patients in hospital on the average by 8 days. A conclusion was made, on the basis of the conducted study, that EET is a pathophysiologically substantiated treatment method for IIS, stage 2, in children with appendicular peritonitis; EET ensures a rapid recovery of gastric-tract functions, it reduces the frequency rate of postoperative complications and cuts the length of both the infusive therapy and of the patients' stay in hospital.
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