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Related Experiment Videos

Axial flow blood pumps.

Xinwei Song1, Amy L Throckmorton, Alexandrina Untaroiu

  • 1Mechanical and Aerospace Engineering Department, Virginia Artificial Heart Institute University of Virginia, Charlottesville, VA, USA.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)
|August 16, 2003
PubMed
Summary

Thousands of cardiac patients needing heart transplants rely on mechanical support. This article reviews axial flow ventricular assist devices (VADs), exploring their design and clinical use for bridge-to-transplant and destination therapy.

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Area of Science:

  • Cardiovascular Medicine
  • Biomedical Engineering
  • Medical Devices

Background:

  • Thousands of patients annually require heart transplantation.
  • A significant shortage of donor hearts limits transplant availability.
  • Mechanical circulatory support, such as left ventricular assist devices (LVADs), is crucial for patients awaiting transplants.

Purpose of the Study:

  • To explore the design and development of axial flow ventricular assist devices (VADs).
  • To review experimental and clinical experiences with various axial flow VAD systems.
  • To assess the potential of these devices for bridge-to-transplant and destination therapy.

Main Methods:

  • Review of design principles for axial flow VADs.
  • Analysis of experimental data and clinical outcomes for specific devices.

Related Experiment Videos

  • Comparative overview of leading axial flow VAD systems.

    • Main Results:

    • Several axial flow VADs have been developed, including Hemopump, MicroMed DeBakey VAD, Jarvik 2000, HeartMate II, Streamliner, Impella, Berlin INCOR I, Valvo pump, and IVAP.
    • These devices show varying degrees of success in providing circulatory support.
    • Clinical data indicates promise for these devices in managing end-stage heart failure.

    Conclusions:

    • Axial flow VADs represent a promising technological advancement in mechanical circulatory support.
    • These devices offer viable options for patients awaiting heart transplantation.
    • Further development and clinical application of axial flow VADs could expand treatment for advanced cardiac failure.