Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

High ionic strength glucose-sensing photonic crystal.

Vladimir L Alexeev1, Anjal C Sharma, Alexander V Goponenko

  • 1Department of Chemistry, Chevron Science Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

Analytical Chemistry
|August 16, 2003
PubMed
Summary

A novel hydrogel material changes color in response to glucose levels. This colorimetric glucose sensor shows potential for noninvasive monitoring in diabetes management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Knowledge, Benefits, and Challenges of ChatGPT Use in Education Among Nursing Students: A Descriptive, Cross-Sectional Study.

Creative nursing·2026
Same author

Spatially distributed complex organic matter detected in an ancient river valley in Jezero crater, Mars.

Science advances·2026
Same author

Evaluating the therapeutic impact of early multimodal rehabilitation in hemiplegic stroke patients: A quasi-experimental study.

Scientific reports·2026
Same author

MAGMAS Inhibition Enhances Temozolomide Efficacy in Chemotherapy-Resistant Glioblastoma Models.

Cancer research communications·2026
Same author

When care demands rise: Exploring the impact of hemiparesis dependency and healthcare challenges among caregivers at a tertiary hospital in Bhubaneswar.

Journal of education and health promotion·2026
Same author

Nursing care challenges and overcoming strategies among stroke patients.

Journal of education and health promotion·2026

Area of Science:

  • * Materials Science and Engineering
  • * Biomedical Engineering
  • * Analytical Chemistry

Background:

  • * Accurate glucose monitoring is crucial for diabetes management.
  • * Current methods for glucose sensing can be invasive or inconvenient.
  • * Developing novel, noninvasive glucose detection materials is a significant challenge.

Purpose of the Study:

  • * To develop a colorimetric glucose recognition material using a photonic crystal hydrogel.
  • * To investigate a new molecular recognition motif for glucose sensing.
  • * To assess the material's performance at physiological conditions and its selectivity.

Main Methods:

  • * Fabrication of a hydrogel embedded with a crystalline colloidal array, incorporating phenylboronic acid and poly(ethylene glycol) (PEG) or crown ether functional groups.

Related Experiment Videos

  • * Utilizing a supramolecular complex formation triggered by glucose to alter hydrogel cross-linking.
  • * Observing color shifts in the photonic crystal diffraction in response to varying glucose concentrations.

    • Main Results:

    • * Glucose binding induced a blue shift in the photonic crystal diffraction, causing a visible color change.
    • * The material exhibited a color shift across the visible spectrum at physiologically relevant glucose concentrations.
    • * The hydrogel demonstrated selective response to glucose over other sugars (galactose, mannose, fructose) at physiological pH and ionic strength.

    Conclusions:

    • * A new molecular recognition motif for glucose sensing has been successfully developed.
    • * The developed hydrogel material shows promise for noninvasive or minimally invasive in vivo glucose sensing.
    • * This technology could significantly benefit patients with diabetes mellitus through improved monitoring.