Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Adhesive crosstalk in gastrulation.

Juan-Antonio Montero1, Carl-Philipp Heisenberg

  • 1Max-Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr. 108, 01307, Dresden, Germany.

Developmental Cell
|August 16, 2003
PubMed
Summary

Integrin receptors are crucial for cell movement in Xenopus gastrulation. These receptors regulate cadherin activity, impacting tissue development during convergence and extension.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Active and probe-free intracellular rheology via phase-sensitive thermoviscous flows.

PNAS nexus·2026
Same author

Keratins coordinate tissue spreading by balancing spreading forces with tissue material properties.

Nature communications·2026
Same author

Decoding zebrafish oogenesis: From primordial germ cell development to fertilization.

Seminars in cell & developmental biology·2025
Same author

Hoxb genes determine the timing of cell ingression by regulating cell surface fluctuations during zebrafish gastrulation.

Development (Cambridge, England)·2025
Same author

BMP-dependent patterning of ectoderm tissue material properties modulates lateral mesendoderm cell migration during early zebrafish gastrulation.

Cell reports·2025
Same author

Development: Turing mechanics.

Current biology : CB·2024

Area of Science:

  • Developmental biology
  • Cell biology

Background:

  • Cellular movements are essential for embryonic development.
  • Integrin and cadherin molecules play key roles in cell adhesion and migration.

Purpose of the Study:

  • To investigate the role of integrin signaling in Xenopus gastrulation.
  • To understand how integrins modulate cadherin activity during embryonic tissue movements.

Main Methods:

  • Utilizing Xenopus laevis as a model organism.
  • Employing molecular and cellular techniques to study cell migration and adhesion.

Main Results:

  • Integrin receptor signaling is necessary for proper cell movements during Xenopus gastrulation.
  • Integrins influence the activity of cadherin adhesion molecules in developing tissues.

Conclusions:

  • Integrin-mediated signaling is a critical regulator of cell-cell interactions and tissue morphogenesis.
  • The interplay between integrins and cadherins is vital for convergence and extension movements in early vertebrate development.

Related Experiment Videos