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Permanent interstitial brachytherapy for prostate cancer: a current review
Jeffrey Woolsey1, Nicole Miller, Dan Theodorescu
1Department of Urology, University of Virginia Health Sciences Center, Box 422, Charlottesville, VA 22908, USA.
World Journal of Urology
|August 16, 2003
Summary
Prostate brachytherapy offers a popular, outpatient treatment for prostate cancer with potentially lower risks of incontinence and erectile dysfunction. This review covers its history, techniques, and outcomes for cancer control and quality of life.
Area of Science:
- Oncology
- Radiation Oncology
- Urology
Background:
- Prostate brachytherapy using permanent radioactive implants is a growing treatment option for prostate cancer.
- It is favored for its outpatient nature and potential for reduced long-term urinary incontinence and erectile dysfunction compared to other treatments.
Purpose of the Study:
- To review the history, isotopes, implantation techniques, and outcomes of modern prostate brachytherapy.
- To discuss cancer control and health-related quality of life endpoints associated with this therapy.
Main Methods:
- This is a review article.
- It synthesizes information on the historical development of prostate brachytherapy.
- It examines current implantation techniques and radioactive isotopes utilized.
Main Results:
- Modern prostate brachytherapy is an increasingly popular choice for prostate cancer patients.
- The procedure is performed on an outpatient basis.
- Associated with potentially lower long-term risks of urinary incontinence and erectile dysfunction.
Conclusions:
- Prostate brachytherapy is a viable and increasingly adopted treatment for prostate cancer.
- Outcomes in terms of cancer control and quality of life are key considerations.
- Further research and technique refinement continue to improve patient outcomes.