Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Specific infectious complications after stem cell transplantation.

Holger Hebart1, Hermann Einsele

  • 1Department of Hematology and Oncology, University of Tübingen, Germany. hrhebart@med.uni-tuebingen.de

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
|August 16, 2003
PubMed
Summary

Infectious complications after stem cell transplantation (SCT) are a major cause of death. Advances in SCT care have improved outcomes by controlling infections and reducing mortality.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

European Myeloma Network perspective on CAR T-Cell therapies for multiple myeloma.

Haematologica·2021
Same author

Expert review on soft-tissue plasmacytomas in multiple myeloma: definition, disease assessment and treatment considerations.

British journal of haematology·2021
Same author

Novel molecular subgroups within the context of receptor tyrosine kinase and adhesion signalling in multiple myeloma.

Blood cancer journal·2021
Same author

Treatment of relapsed and refractory multiple myeloma: recommendations from the International Myeloma Working Group.

The Lancet. Oncology·2021
Same author

Proof of concept for a rapidly switchable universal CAR-T platform with UniCAR-T-CD123 in relapsed/refractory AML.

Blood·2021
Same author

Idecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma.

The New England journal of medicine·2021

Area of Science:

  • Hematology
  • Transplantation Immunology
  • Infectious Diseases

Background:

  • Infectious complications are a primary cause of morbidity and mortality following stem cell transplantation (SCT).
  • Key factors influencing infection risk and outcomes include the stem cell source and the post-transplant thời gian.
  • Historically, infections posed a significant challenge to SCT success.

Purpose of the Study:

  • To review the impact of recent advancements on infectious complications after SCT.
  • To discuss the evolving epidemiology and management strategies for post-transplant infections.
  • To highlight the reduction in transplant-related mortality due to improved infection control.

Main Methods:

  • Review of recent developments in preparative regimens and graft manipulation.

Related Experiment Videos

  • Analysis of the impact of prophylaxis and preemptive treatment strategies.
  • Examination of changes in the timing and epidemiology of infections post-SCT.

    • Main Results:

    • Effective prophylaxis and preemptive treatments have significantly altered infection patterns.
    • Advancements in SCT care have led to better control of infectious complications.
    • Reduced transplant-related mortality has been observed.

    Conclusions:

    • Improved management of infectious complications is crucial for successful SCT.
    • The epidemiology of infections post-SCT has shifted due to therapeutic advancements.
    • Enhanced control strategies have demonstrably decreased mortality associated with SCT.