Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Controversies in chicken-pox immunization.

Swati Y Bhave1

  • 1Indraprastha Apollo Hospital & Max Health Care, New Delhi, India. sybhave@vsnl.com

Indian Journal of Pediatrics
|August 19, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Primary ciliary dyskinesia in pediatric persons: A microscopic movement malady.

Disease-a-month : DM·2026
Same author

The Health Effects of Climate Change on Children: Pediatricians Must Be Part of the Solution.

Indian pediatrics·2023
Same author

Role of Psychologist in Adolescent Medicine: An International Perspective.

Pediatric clinics of North America·2022
Same author

Pediatric Residency Training for Integration of Behavior Health: Indian Perspective.

Pediatric clinics of North America·2021
Same author

E-cigarettes and Vaping: A Global Risk for Adolescents.

Indian pediatrics·2021
Same author

International Adolescent Health Week Inspires Adolescents and Their Communities to Advocate for a Successful Transition Into Adulthood.

The Journal of adolescent health : official publication of the Society for Adolescent Medicine·2020

Chicken-pox vaccination is safe and effective, offering significant cost benefits. Routine childhood immunization programs are crucial for disease control, but WHO currently doesn't recommend it for developing countries.

Area of Science:

  • * Infectious Diseases
  • * Vaccinology
  • * Public Health

Background:

  • * Chickenpox (varicella) is a highly contagious disease affecting most children and young adults globally.
  • * Prior to vaccine availability in the US (1990-1994), there were ~4 million cases annually, with 10,000 hospitalizations and 100 deaths.
  • * The socioeconomic impact of varicella, including work absence, is substantial and often underestimated.

Purpose of the Study:

  • * To evaluate the safety, efficacy, and cost-benefit of varicella vaccination.
  • * To assess the impact of vaccination strategies on disease epidemiology.
  • * To inform recommendations for varicella vaccine inclusion in national immunization programs.

Main Methods:

  • * Review of existing data on varicella incidence, hospitalization, and mortality.

Related Experiment Videos

  • * Analysis of cost-benefit studies for varicella vaccination in the USA.
  • * Epidemiological modeling of vaccination impacts at individual and population levels.

    • Main Results:

    • * Varicella vaccines are safe and effective.
    • * A US cost-benefit analysis indicated routine vaccination could yield five times the investment, with direct costs nearly balanced by benefits.
    • * Vaccinating adolescents/adults protects individuals but has minimal population-level epidemiological impact; routine childhood vaccination significantly impacts disease spread.

    Conclusions:

    • * Routine childhood varicella immunization programs require high, sustained coverage to potentially eliminate the disease.
    • * Partial coverage may shift the epidemiology, increasing cases in older age groups.
    • * WHO does not currently recommend varicella vaccine for routine immunization in developing countries due to lower priority compared to diseases with greater socioeconomic impact.